Supplements & Compounds
Which supplements actually have human data - and which are still stuck in mouse studies. Each entry reviews the mechanism, dosing, side effects and clinical trials.
Topics in Supplements & Compounds
24 articles
Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) are two prominent NAD+ precursors that have gained attention for their potential role in promoting longevity. This article examines the current evidence from human trials to clarify their effects on health and aging.
Resveratrol, a compound found in red wine, has garnered attention for its potential health benefits. This article delves into the human data, mechanisms of action, and the reality behind the claims surrounding resveratrol supplementation.
Rapamycin has emerged as a leading candidate in the pursuit of longevity, showing potential to extend lifespan and improve healthspan. This article delves into its mechanisms, evidence from human studies, and safety considerations.
Spermidine, a natural polyamine, has garnered attention for its potential role in promoting autophagy and longevity. This article delves into the human observational data supporting its benefits and mechanisms of action.
GlyNAC, a combination of glycine and N-acetylcysteine, is being investigated for its potential to restore glutathione levels. This article explores the evidence from GlyNAC trials and its implications for longevity and health.
Explore the potential of GlyNAC, a combination of glycine and NAC, in restoring glutathione levels. This article delves into the GlyNAC trials, their findings, and implications for health and longevity.
Recent studies highlight taurine's potential as a key nutrient for promoting longevity. This article delves into the latest findings and their implications for health and aging.
Vitamin D and K2 are essential nutrients that play pivotal roles in maintaining bone health and cardiovascular function. This article explores their dosing guidelines, optimal blood levels, and the synergistic effects they have when taken together.
An evidence-based look at NMN and NR: what the human trials actually show as part of our NMN & NR guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at NAD+ and aging: is supplementation worth it as part of our NMN & NR guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at The NMN-longevity case, graded on evidence as part of our NMN & NR guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Resveratrol: the hype, the data, the mechanism as part of our Resveratrol guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Why the resveratrol story fell apart as part of our Resveratrol guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Rapamycin: the most promising longevity drug in humans as part of our Rapamycin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Rapamycin dosing protocols and weekly pulsing as part of our Rapamycin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Rapamycin side effects: what the trials show as part of our Rapamycin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at mTOR inhibition and the longevity trade-offs as part of our Rapamycin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Metformin for longevity: what TAME is testing as part of our Metformin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Does metformin blunt exercise adaptations as part of our Metformin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Metformin mechanisms: beyond blood glucose as part of our Metformin guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Spermidine: the autophagy-inducing longevity nutrient as part of our Spermidine guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Spermidine food sources vs supplementation as part of our Spermidine guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at The spermidine observational evidence as part of our Spermidine guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at GlyNAC: glycine + NAC for longevity as part of our Glycine & NAC (GlyNAC) guide in Supplements & Compounds. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.