Diseases of Aging
Heart disease, cancer, neurodegeneration and metabolic disease share aging itself as their biggest risk factor. Targeting aging directly may be the most leveraged way to prevent them.
Topics in Diseases of Aging
22 articles
Atherosclerosis is a leading cause of cardiovascular disease, significantly contributing to mortality worldwide. This article delves into the role of apolipoprotein B (ApoB) in atherosclerosis and its implications for public health.
Insulin resistance and metabolic syndrome have significant implications for longevity and overall health. This article explores the evidence linking these conditions to aging and offers insights into potential interventions for better health outcomes.
Osteoporosis is a significant health concern, particularly in aging populations, leading to increased fracture risk. This article explores the relationship between bone density, fracture risk, and the role of mechanical loading in maintaining bone health.
Osteoporosis is a significant concern for aging populations, characterized by reduced bone density and increased fracture risk. This article explores the mechanisms behind osteoporosis, highlighting the importance of bone loading and preventative measures to maintain skeletal health.
An evidence-based look at Atherosclerosis and aging: the real #1 killer as part of our Cardiovascular Disease guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Why ApoB is a better predictor than LDL-C as part of our Cardiovascular Disease guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at The longevity-first approach to cardiovascular disease as part of our Cardiovascular Disease guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Alzheimer's disease: the amyloid hypothesis and its rivals as part of our Neurodegeneration guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at What Peter Attia calls "the Centenarian Decathlon" for the brain as part of our Neurodegeneration guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Early warning biomarkers for Alzheimer's risk as part of our Neurodegeneration guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Why cancer risk rises exponentially with age as part of our Cancer & Aging guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at The two-hit hypothesis and somatic mutations as part of our Cancer & Aging guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Cancer screening for longevity: what's worth doing as part of our Cancer & Aging guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Metabolic syndrome: the quiet longevity killer as part of our Type 2 Diabetes & Metabolic Syndrome guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at How insulin resistance accelerates aging as part of our Type 2 Diabetes & Metabolic Syndrome guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Reversing type 2 diabetes: the human evidence as part of our Type 2 Diabetes & Metabolic Syndrome guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Sarcopenia: why muscle loss is a longevity emergency as part of our Sarcopenia & Frailty guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Grip strength as a mortality predictor as part of our Sarcopenia & Frailty guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Protein, resistance training and preserving muscle after 50 as part of our Sarcopenia & Frailty guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Bone density and the longevity link nobody talks about as part of our Osteoporosis guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Weight-bearing exercise for bone: the minimum effective dose as part of our Osteoporosis guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at DEXA scans, T-scores and when to screen as part of our Osteoporosis guide in Diseases of Aging. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.