Hallmarks of Aging
The canonical hallmarks framework of Lopez-Otin et al.
5 articles
The hallmarks of aging proposed by López-Otín and colleagues serve as a comprehensive framework for understanding the biological processes that contribute to aging. This article explores each hallmark, its implications for longevity research, and the current evidence supporting these concepts.
An evidence-based look at The 12 hallmarks of aging, explained in plain English as part of our Hallmarks of Aging guide in Aging Biology. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at From 9 to 12: how the hallmarks framework was updated in 2023 as part of our Hallmarks of Aging guide in Aging Biology. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at Which hallmarks of aging matter most for humans as part of our Hallmarks of Aging guide in Aging Biology. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.
An evidence-based look at How the hallmarks framework shaped the last decade of longevity research as part of our Hallmarks of Aging guide in Aging Biology. What the human research actually shows, the strongest mechanistic case, and what it means for healthspan.